The Joe K. and Alberta Blanton Nursing Building opened in Spring 2009 and replaced the previous nursing building on Johnson Avenue. Alberta Blanton donated $2.5 million in funds for this building as a memorial to her late husband and to enhance the overall nursing program at Florida Southern College. In 2014, the building received further renovations including the installation of laboratory space, offices, and two new classrooms. The building was expanded again in 2015 with the opening of the second floor. In 2021, the Joe K. and Alberta Blanton Nursing Building became the home of the undergraduate program of the Ann Blanton Edwards School of Nursing and Health Sciences, named for the daughter of Alberta and Joe.